Category: Pentobarbital Barbiturates

Pentobarbital Barbiturates

Pentobarbital Barbiturates is a short-acting barbiturate that is used as hypnotic and anticonvulsant as the sodium salt. It has been used in short-term management of insomnia and premedication in anesthetic procedures. Pentobarbital is commonly used as an anesthetic in veterinary medicine and in small animal studies.

What’s the difference between phenobarbital and pentobarbital?

Oral and rectal phenobarbital acts within 20 to 60 minutes. Metabolism: Pentobarbital undergoes first-pass metabolism in the liver. Pentobarbital is metabolized predominantly by the hepatic microsomal enzymes.

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Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as well as overdose potential among other possible adverse effects. They have been used recreationally for their anti-anxiety and sedative effects, and are thus controlled in most countries due to the risks associated with such use.

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